Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
0.400 GeneticVariation disease BEFREE • The glioblastoma subgroup was stratified according to MGMT promoter methylation status. 27048531 2017
Entrez Id: 546
Gene Symbol: ATRX
ATRX
0.380 GeneticVariation disease BEFREE • Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients. 29721688 2018
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.500 GeneticVariation disease BEFREE • Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients. 29721688 2018
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
0.400 GeneticVariation disease BEFREE • Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients. 29721688 2018
Entrez Id: 113451
Gene Symbol: AZIN2
AZIN2
0.100 Biomarker disease BEFREE • Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients. 29721688 2018
Entrez Id: 339896
Gene Symbol: GADL1
GADL1
0.100 Biomarker disease BEFREE • Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients. 29721688 2018
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
0.400 PosttranslationalModification disease BEFREE • ASL-PWI can aid to predict IDH and MGMT promoter methylation statuses in GBM. 31468161 2020
Entrez Id: 435
Gene Symbol: ASL
ASL
0.060 GeneticVariation disease BEFREE ASL-PWI performs well (AUC > 0.8) in differentiating PCNSL from GBM. 29619520 2018
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
0.400 Biomarker disease BEFREE GBMs with unmethylated MGMT promoter present higher APTw-MRI than methylated GBMs. 29234914 2018
Entrez Id: 2806
Gene Symbol: GOT2
GOT2
0.010 Biomarker disease BEFREE ω-3 and ω-6 Fatty Acids Modulate Conventional and Atypical Protein Kinase C Activities in a Brain Fatty Acid Binding Protein Dependent Manner in Glioblastoma Multiforme. 29642372 2018
Entrez Id: 2114
Gene Symbol: ETS2
ETS2
0.020 Biomarker disease BEFREE ΔNp73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma. 31763674 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.500 Biomarker disease BEFREE ΔEGFR is a potent glioblastoma oncogene which has been studied primarily as a plasma membrane kinase. 23250739 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.500 AlteredExpression disease BEFREE ΔEGFR cooperated with STAT5b to regulate the Bcl-XL promoter and knockdown of STAT5b suppressed anchorage independent growth, reduced the levels of Bcl-XL and sensitized glioblastoma cells to cisplatin. 22729867 2013
Entrez Id: 998
Gene Symbol: CDC42
CDC42
0.060 Biomarker disease BEFREE αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion. 23283986 2013
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.100 Biomarker disease BEFREE αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion. 23283986 2013
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 AlteredExpression disease BEFREE [Retracted] FOXO1 is crucial in glioblastoma cell tumorigenesis and regulates the expression of SIRT1 to suppress senescence in the brain. 29286123 2018
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.080 Biomarker disease BEFREE [Retracted] FOXO1 is crucial in glioblastoma cell tumorigenesis and regulates the expression of SIRT1 to suppress senescence in the brain. 29286123 2018
Entrez Id: 9860
Gene Symbol: LRIG2
LRIG2
0.050 Biomarker disease BEFREE [Corrigendum] LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling. 30942453 2019
Entrez Id: 27087
Gene Symbol: B3GAT1
B3GAT1
0.010 AlteredExpression disease BEFREE [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(1⁻11), [<sup>177</sup>Lu]DOTA-SP(4⁻11) and [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(5⁻11) radiobioconjugates bound specifically to NK-1 receptors expressed on glioblastoma cells with affinity in the nanomolar range. 30301182 2018
Entrez Id: 11126
Gene Symbol: CD160
CD160
0.010 AlteredExpression disease BEFREE [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(1⁻11), [<sup>177</sup>Lu]DOTA-SP(4⁻11) and [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(5⁻11) radiobioconjugates bound specifically to NK-1 receptors expressed on glioblastoma cells with affinity in the nanomolar range. 30301182 2018
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.050 Biomarker disease BEFREE [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(1⁻11), [<sup>177</sup>Lu]DOTA-SP(4⁻11) and [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(5⁻11) radiobioconjugates bound specifically to NK-1 receptors expressed on glioblastoma cells with affinity in the nanomolar range. 30301182 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.400 Biomarker disease BEFREE Zymography analysis also revealed that the activities of MMP-2 and MMP-9 of GBM cells were significantly inhibited in response to 100, 200, or 300 μM naringenin treatment. 30431227 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.400 Biomarker disease BEFREE Zymography analysis also revealed that the activities of MMP-2 and MMP-9 of GBM cells were significantly inhibited in response to 100, 200, or 300 μM naringenin treatment. 30431227 2019
Entrez Id: 23354
Gene Symbol: HAUS5
HAUS5
0.010 AlteredExpression disease BEFREE ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5. 28596487 2017
Entrez Id: 407042
Gene Symbol: MIR34C
MIR34C
0.020 AlteredExpression disease BEFREE Zika virus infection induces MiR34c expression in glioblastoma stem cells: new perspectives for brain tumor treatments. 30890698 2019